A recent John Hopkins study has established that the use of synthetic psychedelic 5-methocy-N,-N-dimethyltryptamine (5-MeO-DMT) is related to unintentional improvement in self-reported anxiety and depression. 5-MeO-DMT is a psychedelic found in Bufo Alvarious toad’s venom, different plant species, and synthetically produced.
5-MeO-DMT can improve depression and anxiety outcomes
Survey results of 362 individuals showed that 80% had improved depression and anxiety responses after using 5-MeO-DMT. The improvements were associated with acute mystic effects during the experience with the psychedelic. There was also an enhanced rating in personal spiritual significance and meaning with the 5-MeO-DMT experience. The individuals’ improvement correlated with strong beliefs that the experience results in lasting wellbeing and life satisfaction. John Hopkins published the study results in The American Journal of Drug and Alcohol Abuse.
5-MeO-DMT acts very fast and produces psychedelic effects within a short time compared to other psychedelics. Post-doctoral research fellow at Johns Hopkins University School of Medicine, Alan K Davis, indicated that studies show that when psychedelics are given alongside psychotherapy, they help alleviate anxious feelings and depression. Interestingly psychedelics require around 7 to 8 hours for each session since they have a long period of action. Davis said that 5-MeO-DMT is a short-acting psychedelic that lasts around 30 to 90 minutes. Therefore it is easier to use as a therapy adjunct than current therapies involving a 60 to 90 minutes session.
More studies showing 5-MeO-DMT’s psychedelic effects
In 2019, Davis published a study in Frontiers in Psychology that showed that 5-MeO-DMT administration in psychospiritual retreat circumstance produced significant mystical experience rating as a high psilocybin dose session in a lab. In another study, Davis demonstrated that 5-MeO-DMT had a favorable safety profile with low health risk and legal consequences.
Davis says that it is essential to evaluate the long- and short-term impact of 5-MeO-DMT as a mood enhancer or a mood-enhancing component for individuals experiencing a negative mood. However, research is still in infancy, and therefore more studies are necessary for healthy volunteers to demonstrate this.
